Venegas-Calerón, Mónica Sayanova, Olga Napier, Johnathan A PMID:24618601Īn alternative to fish oils: Metabolic engineering of oil-seed crops to produce omega- 3 long chain polyunsaturated fatty acids. Such advances can assist with preventative health care, fisheries management, aquaculture nutrition, an innovative feed/food industry and ultimately towards improved consumer health. The development and future application of oilseeds containing LC omega- 3 oils and their incorporation in aquafeeds would allow these health-benefitting oils to be maximized in farmed Australian seafood. Australian consumers increasingly seek their LC omega- 3 from supplements, therefore a range of supplement products were compared. Sum of EPA and DHA concentrations in RBC, the omega- 3 index, was increased following krill oil supplementation compared with fish oil (p = 0.0143) and control (p 5:1 to 5:1 to <1:1). Krill oil consumption increased plasma (p = 0.0043) and RBC (p = 0.0011) n- 3 PUFA concentrations, including EPA and DHA, and reduced n-6:n- 3 PUFA ratios (plasma: p = 0.0043, RBC: p = 0.0143) compared with fish oil consumption. Each treatment lasted 4 wk and was separated by 8 wk washout phases. The study consisted of three treatment phases including krill or fish oil each providing 600 mg of n- 3 polyunsaturated fatty acids (PUFA) or placebo control, corn oil in capsule form. Twenty four healthy volunteers were recruited for a double blinded, randomized, placebo-controlled, crossover trial. The objective was to assess the effects of krill oil compared with fish oil or a placebo control on plasma and red blood cell (RBC) fatty acid profile in healthy volunteers. Ramprasath, Vanu R Eyal, Inbal Zchut, Sigalit Jones, Peter J Hĭue to structural differences, bioavailability of krill oil, a phospholipid based oil, could be higher than fish oil, a triglyceride-based oil, conferring properties that render it more effective than fish oil in increasing omega- 3 index and thereby, reducing cardiovascular disease (CVD) risk. The hydrolytic stability was shown not to be a problem during the storage of any of the oils.Įnhanced increase of omega- 3 index in healthy individuals with response to 4-week n- 3 fatty acid supplementation from krill oil versus fish oil. The microalgal HI oils were shown to be more oxidatively stable than the microalgal H oils. When the results of both the primary and secondary oxidation parameters were put together, it was clear that fish, tuna, and heterotrophic microalgae oil are the least oxidatively stable oils, whereas krill oil and the microalgae oils performed better. The purpose of this work was therefore to evaluate these parameters in oils from photoautotrophic microalgae (Isochrysis, Phaeodactylum, Nannochloropsis gaditana, and Nannochloropsis sp.) obtained with hexane/isopropanol (HI) and hexane (H) and compare them with commercial omega- 3 LC-PUFA oils. However, oxidative and hydrolytic stability of omega- 3 LC-PUFA oils are important parameters. Their oil may thus be a potential alternative for fish oil. Microalgae are the primary producers of omega- 3 LC-PUFA, which are known for their health benefits. Ryckebosch, Eline Bruneel, Charlotte Termote-Verhalle, Romina Lemahieu, Charlotte Muylaert, Koenraad Van Durme, Jim Goiris, Koen Foubert, Imogen Stability of omega- 3 LC-PUFA-rich photoautotrophic microalgal oils compared to commercially available omega- 3 LC-PUFA oils.
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